A Case of Peripheral Polyneuropathy Presenting with Central Retinal Artery Occlusion, Rapid Progressive Glomerulonephritis due to ANCA Associated Vasculitis

doi:2018.20.1.72

J Electrodiagn Neuromuscul Dis > Volume 20(1); 2018 > Article

Case Report

J Korean Assoc EMG Electrodiagn Med 2018;20(1):72-76.
DOI: https://doi.org/10.18214/jkaem.2018.20.1.72 Published online June 30, 2018.

A Case of Peripheral Polyneuropathy Presenting with Central Retinal Artery Occlusion, Rapid Progressive Glomerulonephritis due to ANCA Associated Vasculitis

Received: 6 April 2018 • Revised: 16 May 2018 • Accepted: 1 June 2018

Abstract

We report a case of asymmetric polyneuropathy with left central retinal artery occlusion, rapid progressive glomerulonephritis (RPGN) due to Antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV). A-64-year-old man started to have numbness and weakness in both legs. One month later, he suddenly lost a vision in his left eye and had swelling in both legs. Thereafter, weakness progressed to both upper extremities. Multiple eye retinal hemorrhages and cherry-red spots were observed on fundus examination and were diagnosed as central retinal artery occlusion. Pauci-immune crescentic glomerulonephritis were identified after renal biopsy. Nerve conduction study was performed and the patient was diagnosed by peripheral polyneuropathy involving both upper and lower extremities. Clinically, we diagnosed a vasculitis, especially microscopic polyangiitis (MPA).

Key Words: antineutrophil cytoplasmic antibody, central retinal artery occlusion, polyneuropathy