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J Korean Assoc EMG Electrodiagn Med 2015;17(2):86-88.
Published online December 31, 2015.
Myasthenia Gravis Accompanied by Adrenal Gland Tumor -A Case Report -
Received: 13 August 2015   • Revised: 10 September 2015   • Accepted: 10 September 2015
Abstract
It is unknown that hormone secreting adrenal gland can cause myasthenia gravis. Case: 55 year old man visited our clinic due to episodic diplopia which aggravated at evening. He had long standing uncontrolled hypertension and taken antihypertensive drug without thiazide. One and 3 year before visiting, he had history of transient quadriparesis with hypokalemia (Potassium level 1.9 mmol/L). Antiacethycholinereceptor antibody test was negative. Repetitive nerve stimulation showed generalized decremental response. Left adrenal gland mass was detected at chest CT scan incidentally. Hormonal test was compatible with primary hyperaldosteronism. Left adrenalectomy was done. Repetitive nerve stimulation test which was taken after surgery did not show decremental response. Active hormone secreting adrenal tumor may be cause of secondary myasthenia gravis. More extensive chest CT scan for cover adrenal glands must need in myasthenia with uncontrolled hypertension.
Key Words: hypokalemic periodic paralysis, myasthenia gravis, primary hyperaldosteronism
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