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J Korean Assoc EMG Electrodiagn Med 2011;13(2):126-130.
Published online December 1, 2011.
Two Cases of Guillain-Barre′Syndrome Following Scrub Typhus - A Case Report -
Received: 11 May 2011   • Revised: 23 June 2011   • Accepted: 27 July 2011
Abstract
Scrub typhus is an acute febrile zoonosis caused by Orientia tsusugamushi, which is transmitted by the infected trombiculid mites. Infections by virulent strains are characterized by fever, rash, eschar, pneumonia, myocarditis and disseminated intravascular coagulation. But peripheral nerve system involvement in scrub typhus is rare. We report two cases of Guillain-Barre′syndrome (GBS) associated with scrub typhus, who initially presented with fever, rash, eschar and responded to doxycyclin. The serological data confirmed the diagnosis of scrub typhus. Two patients later developed ascending progressive weakness that involved both lower and upper extremities. The neurologic examination, cerebrospinal fluid and electromyography studies were compatible with GBS.
Key Words: Scrub typhus, Gullain- Barre′syndrome


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