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J Korean Assoc EMG Electrodiagn Med 2010;12(1):48-50.
Published online June 1, 2010.
Multiple Cranial Neuropathies and Pupillary Areflexia Associated with Anti-GQ1b Antibody
Abstract
The causes of multiple cranial neuropathies are variable, including infection, inflammation or neoplastic lesion. They also can be a presenting features of the atypical variant of the Guillain-Barre syndrome (GBS). In spite of careful clinical investigation, etiology often remains unknown in many cases. We describe a patient who presented with ophthalmoplegia with pupillary areflexia, bulbar dysfunction, and bilateral facial palsy after upper respiratory tract infection and had significant elevation of anti-GQ1b antibody titer. We suggest that pupillary areflexia should be recognized as another feature that may be present in conditions of the anti-GQ1b antibody syndrome.
Key Words: Multiple cranial neuropathies, Pupil, Anti GQ1b antibody
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