The Effect of Subthreshold Repetitive Transcranial Magnetic Stimulation of Motor Cortex on the Sympathetic Skin Response

J Korean Assoc EMG Electrodiagn Med 2007;9(2):116-121.
Published online May 10, 2007.

Abstract

Objectives: To explore the effect of subthreshold intensity repetitive transcranial magnetic stimulations(rTMS) over the primary motor cortex on the sympathetic skin response according to the stimulation frequency. Methods: 1 Hz and 20 Hz rTMS were applied on the motor cortex of the left hand at 90% intensity of resting motor threshold respectively in twelve healthy volunteers. We evaluated sympathetic skin response on the bilateral palms and soles before and immediately, 30 minute and 60 minute after rTMS application. Results: There were no significant changes of latencies and amplitudes of the sympathetic skin response in the both palms and soles after low and high frequency rTMS on the motor cortex. Conclusion: Sub-threshold rTMS over the hand motor cortex does not seem to effect on the sympathetic skin response.

Key Words: Sympathetic skin response, rTMS