The Effect of Glucose Long-Term Control on the Nerve Conduction Parameters in the Diabetic Peripheral Neuropathy

J Korean Assoc EMG Electrodiagn Med 2005;7(2):95-99.
Published online May 10, 2005.

Abstract

Objectives: In order to assess the correlation between the glucose control and the change of nerve conduction in the diabetic peripheral neuropathy. Method: Thirty five patients with diabetic peripheral neuropathy diagnosed by nerve conduction study (NCS) were included and NCS were reexamined later. The values of nerve conduction were evaluated by difference between 1st study and follow-up study. The level of fasting blood glucose is divided to 10 grades and level of HbA1c is divided to 6 grades according to goal of glucose control by American diabetes association. The effect of glucose control on the change of nerve conduction were analyzed by linear regression test. Results: The controlled level of fasting blood glucose had a significant effect on the latencies of median, ulnar motor and sensory nerves and sural sensory nerve. The level of HbA1c had a significant effect on the latency of peroneal motor nerve (p<0.05). Conclusion: The level of fasting blood glucose and HbA1c had a significant effect on the change of nerve conduction latency.

Key Words: Glucose control, Diabetic peripheral neuropathy, Nerve conduction study, Correlation